We primarily use high-resolution single particle cryo-EM to pursue the native structures of macromolecular complexes that are directly isolated from various organisms, ranging from green algae to mammals. Most of our current projects are related to microtubules and cilia.

Doublet Microtubules from Sea Urchin Sperm and Bovine Sperm

Cortical Microtubules from Human Parasite Toxoplasma Gondii

Central Apparatus within the Axoneme

Radial Spokes within the Axoneme

Ciliary Doublet Microtubule from Chlamydomonas